Also Known as Triple Test, Multiple Marker Screening and AFP Plus The triplescreen test is a maternal blood screening test that looks for three specific substances: AFP, hCG, and Estriol. AFP: alpha-fetoprotein is a protein that is produced by the fetus.
A triple marker screen test takes a sample of blood and detects the levels of AFP, HCG, and estriol in it. AFP: A protein produced by the fetus. … Low estriol levels may indicate risk of having a baby with Down syndrome, especially when paired with low AFP levels and high HGC levels.